Among ethers, dibutyl ether has strong solubility and can dissolve many natural and synthetic oils, resins, rubber, organic acid esters, alkaloids, etc. The solubility of dibutyl ether in water (20 ℃) is 0.03% by weight, and the solubility of water in butyl ether (20 ℃) is 0.19% by weight, indicating good separation from water. During storage, it generates minimal amounts of Chemicalbook oxides, with low toxicity and danger, making it a highly safe solvent. Used as an extraction and refining solvent for resins, oils, organic acids, esters, waxes, alkaloids, hormones, etc; A mixed solution with butyl phosphate can be used as a solvent for separating rare earth elements. Due to its inert nature, dibutyl ether can also be used as a solvent for organic synthesis reactions such as Grignard reagents, rubber, pesticides, etc.